This volume comprises the Lecture Notes of the CIMPA/TUBITAK Summer School Arrangements, Local systems and Singularities held at Galatasaray University, Istanbul during June 2007. The volume is intended for a large audience in pure mathematics, including researchers and graduate students working in algebraic geometry, singularity theory, topology and related fields. The reader will find a variety of open problems involving arrangements, local systems and singularities proposed by the lecturers at the end of the school.