It's the thirteenth annual Lou Gehrig awards. Four B-list celebrity virologists vie to claim the Locked In Syndrome cup and get mulched down to form their disease for mass distribution. A disease hipster takes centre stage on a night when a blast from the past threatens to turn his ordered, pus filled life upside down. In order to blow open a deep rooted conspiracy, he must team up with a disgraced one time child star who wants another shot at the big time, and clear his sullied name. Together, they're going to show people the real meaning of a meltdown.