Describes various experimental models of epilepsy. This book studies the reproduction of well-characterized and readily interpretable experimental models of epilepsy to which various molecular biology techniques can be applied.
Methods in Epilepsy Research is a guide for the reproduction of well characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied. It also considers the appropriate application of reductionist techniques to experimental models of epilepsy. TOC:Electroshock. - Chemoconvulsions. - Kindling. - Brain Slice Preparation for Epilepsy Research. - In Vivo Massed Trial Stimulations. - Audiogenic Seizures in the Mouse and Genetically Epilepsy-Prone Rat. - Focal Seizures. - Evaluation of Behavioural Cognitive Deficits Associated With Antiepileptic Drugs. - Diurnal and Circadian Influences on Seizure Response. - Microdialysis Techniques of Epilepsy Research. - Automated EEG Analyses. - Status Epilepticus. - Focal Microinfusions and Consideration of Neuronal Networks in Epilepsy Research. - Genetic Models of Epilepsy.
"A first-rate method book...[The authors] are highly skilled scientists with many years of experience in epilepsy."- Mannfred A. Hollinger, Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis
