The Christian's Great Interest was fist published in 1668, and many editions have appeared since. As it is now almost unobtainable, it is reprinte with the fervent hope that it will have a further wide circulation, and prove a continued blessing to many. Dr. Owen said, "I have written several folios, but there is more divinity in it (The Christian's Great Interest) than in them all." William Guthrie, of Fenwick, was a cousin of the eminent martyr, James Guthrie, who refused a bishopric and died on the scaffold at the Cross of Edinburgh in 1661. William desired to go to the execution of his valued cousin, but was prevented by friends who feared for his life. It was while a student under Samuel Rutherford, and through his instrumentality, that he received a calling to the ministry.